Which statement about PSSM Type 2 is true?

Which statement about PSSM Type 2 is true?

• A. It is not inherited
• B. It is not related to the GYS1 mutation
• C. It is caused by a virus
• D. It is a genetic disease, so foals may be affected

Answer: (D)

Polysaccharide storage myopathy type 2 is a hereditary muscle disorder in horses, where abnormal polysaccharide accumulates in muscle fibers. While type 2 does not arise from the GYS1 gene mutation that causes type 1, it is still a genetic condition, and the trait can be passed from parents to foals. This means foals can be affected if they inherit the predisposition. It is not caused by a virus. So the statement that it is a genetic disease, so foals may be affected, is the true one.

Polysaccharide storage myopathy type 2 is a hereditary muscle disorder in horses, where abnormal polysaccharide accumulates in muscle fibers. While type 2 does not arise from the GYS1 gene mutation that causes type 1, it is still a genetic condition, and the trait can be passed from parents to foals. This means foals can be affected if they inherit the predisposition. It is not caused by a virus. So the statement that it is a genetic disease, so foals may be affected, is the true one.